OPRA Central Monitoring

Centralized Monitoring Built for Modern Clinical Trials

Improve trial performance by up to 30% with monitoring that reduces complexity and keeps your study on track.

Smarter oversight. Stronger trials.

Clarity Where It Counts

Visualize trial data trends, uncover hidden signals, and focus on what matters most with intelligent filtering and automation.

Confidence in Every Decision

Gain full visibility with dynamic data structures, and prove compliance through a clear, auditable evidence trail.

Efficiency Across the Trial Lifecycle

Automate monitoring tasks, streamline review cycles, and free resources for high-value work.

Smarter Oversight

With OPRA, achieve smarter oversight that saves time, reduces risk, and keeps your trials on track.

Key Features of OPRA CM

Study Hub

A single command centre for Key Risk Indicators and Quality Tolerance Limits. Track trends, surface insights, and maintain oversight with ease.

Rules-Based Automation

Automatically generate and update monitoring observations based on your workflows to ensure consistency across teams.

Dynamic Filtering

Analyse data by study, country, site, subject, or endpoint. Spot patterns, investigate anomalies, and act with precision.

Monitoring Toolkit

Plan, review, and track monitoring activities in one integrated workspace. Maintain alignment across stakeholders and ensure nothing is missed.

Why OPRA?

Real-time insights

Availability of up-to-date risk scores

Trend analysis

View evolution of risks over time

Collaboration

Centralized portal to collaborate with stakeholders

Alerts

Customizable alerts

Data visualizations

Customizable data visualizations

Version control

Eradicates duplication

Assign actions

Assign actions to stakeholders

Audit ready

Full discoverability of mitigations after closeout

Why Choose TRI?

Trusted

Dependable software. Genuine trust. TRI delivers, on time, at scale, with clarity.

Responsive

In a rigid industry, we’re the human touch: pragmatic, responsive, and known by name.

Innovative

We lead, not follow. TRI is fast-moving and data-informed, staying ahead of Sponsor and CRO needs.

RBQM Success Stories

"Worldwide’s RBQM team is one of the most experienced CRO teams in the industry. This, coupled with TRI’s best-in-class technology, ensures we can proactively identify and manage risks, meaning improved quality and patient safety, and, in turn, provide a better experience for sponsors and patients."

"What truly set TRI apart from other vendors was their unparalleled commitment to a quality deliverable helping us effectively apply a novel approach to our operations. They achieved a deep understanding of our objectives by partnering with us on a rigorous change management process which culminated in a shared vision for the integration of their risk assessment and central monitoring solution."

"The Worldwide Clinical Trials team is pleased with our continued partnership with TRI and we are excited about the milestone of having 150 clinical trials in TRI's Risk-Based Quality Management platform. This is a key benefit for our customers as it improves data quality, trial efficiency, and patient safety."

"It has been such a wonderful ride with our TRI partners over the last few years developing our RBQM strategy with our Sponsors and Worldwide Clinical Trials Teams! We love working with everyone at TRI and look forward to bigger and better things to come!"